IN THE SPOTLIGHT Mass Cytometry: A High-Throughput Platform to Visualize the Heterogeneity of Acute Myeloid Leukemia
نویسندگان
چکیده
Division of Hematology, Department of Medicine, The Ohio State University, Columbus, Ohio. Corresponding Author: John C. Byrd, The Ohio State University, B304 Starling Loving Hall, 320 West 10th Avenue, Columbus, OH 43210. Phone: 614-293-9321; Fax: 614-293-7526; E-mail: [email protected] doi: 10.1158/2159-8290.CD-15-0905 ©2015 American Association for Cancer Research. Summary: Behbehani and colleagues use mass cytometry to profi le the heterogeneity of acute myeloid leukemia (AML ) as compared with normal hematopoiesis. By using this approach and characterizing leukemic stem cells, important differences in response to chemotherapy between AML subsets can potentially be explained and new targeted approaches considered. Cancer Discov; 5(9); 912–4. ©2015 AACR .
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